Free energy landscapes of DNA and its assemblies: perspectives from coarse-grained modelling

Jonathan P.K. Doye, Ard A. Louis, John S. Schreck, Flavio Romano, Ryan M. Harrison, Majid Mosayebi, Megan C. Engel, Thomas E. Ouldridge

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations

Abstract

This chapter will provide an overview of how characterising free energy landscapes can provide insights into the biophysical properties of DNA, as well as into the behaviour of the DNA assemblies used in the field of DNA nanotechnology. The landscapes for these complex systems are accessible through the use of accurate coarse-grained descriptions of DNA. Particular foci will be the landscapes associated with DNA self-assembly and mechanical deformation, where the latter can arise from either externally imposed forces or internal stresses.

Original languageEnglish
Title of host publicationFrontiers of Nanoscience
PublisherElsevier Ltd
Pages195-210
Number of pages16
DOIs
StatePublished - Jan 2022

Publication series

NameFrontiers of Nanoscience
Volume21
ISSN (Print)1876-2778
ISSN (Electronic)1876-276X

Keywords

  • DNA
  • coarse-graining
  • free energy landscapes

Fingerprint

Dive into the research topics of 'Free energy landscapes of DNA and its assemblies: perspectives from coarse-grained modelling'. Together they form a unique fingerprint.

Cite this