Synthesis of functionalized oxazolines and oxazoles with DAST and deoxo-fluor

Andrew J. Phillips; Yoshikazu Uto; Peter Wipf; Michael J. Reno; David R. Williams

doi:10.1021/ol005777b

Synthesis of functionalized oxazolines and oxazoles with DAST and deoxo-fluor

Andrew J. Phillips, Yoshikazu Uto, Peter Wipf, Michael J. Reno, David R. Williams

Cooperative Programs for the Advancement of Earth System Science

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484 Scopus citations

Abstract

A mild and highly efficient cyclization of β-hydroxy amides to oxazolines is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from β-hydroxy amides is also presented.

Original language	English
Pages (from-to)	1165-1168
Number of pages	4
Journal	Organic Letters
Volume	2
Issue number	8
DOIs	https://doi.org/10.1021/ol005777b
State	Published - Apr 20 2000

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@article{8666ba309376446db36abe09c97db698,

title = "Synthesis of functionalized oxazolines and oxazoles with DAST and deoxo-fluor",

abstract = "A mild and highly efficient cyclization of β-hydroxy amides to oxazolines is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from β-hydroxy amides is also presented.",

author = "Phillips, \{Andrew J.\} and Yoshikazu Uto and Peter Wipf and Reno, \{Michael J.\} and Williams, \{David R.\}",

year = "2000",

month = apr,

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doi = "10.1021/ol005777b",

language = "English",

volume = "2",

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journal = "Organic Letters",

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publisher = "American Chemical Society",

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T1 - Synthesis of functionalized oxazolines and oxazoles with DAST and deoxo-fluor

AU - Phillips, Andrew J.

AU - Uto, Yoshikazu

AU - Wipf, Peter

AU - Reno, Michael J.

AU - Williams, David R.

PY - 2000/4/20

Y1 - 2000/4/20

N2 - A mild and highly efficient cyclization of β-hydroxy amides to oxazolines is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from β-hydroxy amides is also presented.

AB - A mild and highly efficient cyclization of β-hydroxy amides to oxazolines is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from β-hydroxy amides is also presented.

UR - https://www.scopus.com/pages/publications/0034689867

U2 - 10.1021/ol005777b

DO - 10.1021/ol005777b

M3 - Article

C2 - 10804580

AN - SCOPUS:0034689867

SN - 1523-7060

VL - 2

SP - 1165

EP - 1168

JO - Organic Letters

JF - Organic Letters

IS - 8

ER -

Synthesis of functionalized oxazolines and oxazoles with DAST and deoxo-fluor

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