The Fourth Convection and Moisture Experiment (CAMEX 4) was a scientific field experiment based in Florida in summer 2001 focused on the study of hurricanes off the east coast of the United States. Sponsored by the National Aeronautics and Space Administration's Earth Science Enterprise, and conducted in collaboration with the National Oceanic and Atmospheric Administration's annual hurricane research program, CAMEX 4 utilized aircraft, ground-based and satellite instrumentation to obtain unprecedented, three dimensional characterizations of these important storms. The Aerosonde UAV was selected by NASA to participate in CAMEX 4 because it provided a unique capability to obtain measurements in the atmospheric boundary layer in and around the storms, unattainable by other platforms or measurement capabilities. This paper focuses on the NASA review process that was followed to coordinate the UAV activity with the conventional aircraft operations, as well as with the other participating agencies and the FAA.